David Manuel, an enrolled member of Red Lake Nation and an advocate for producing marijuana, argues that the industry would provide an economic opportunity for Red Lake.

"It's about sovereignty, it's about being who we are and being in charge of our own destiny," Manuel said.

Red Lake Indian Reservation is the only closed reservation in the state and spans more than 1,200 square miles. Manuel said the tribe's large land holdings give it an advantage over other businesses that may seek to grow marijuana.

"We are Anishinaabe, we have a unique world view," Manuel said. "Personally, I'm asked to go gather medicines for my elders, and whoever is sick, out in the woods. These plants are medicine, and to not make these things available is criminal."